{"id":25483,"date":"2021-07-10T01:22:54","date_gmt":"2021-07-09T17:22:54","guid":{"rendered":"https:\/\/www.stroke.org.hk\/home\/?p=25483"},"modified":"2021-07-25T16:38:04","modified_gmt":"2021-07-25T08:38:04","slug":"q-%e6%89%8b%e8%a1%93%e5%89%8d%e9%9c%80%e8%a6%81%e5%81%9c%e6%96%b0%e5%9e%8b%e8%96%84%e8%a1%80%e8%97%a5%e5%97%8e","status":"publish","type":"post","link":"https:\/\/www.stroke.org.hk\/home\/2021\/07\/10\/q-%e6%89%8b%e8%a1%93%e5%89%8d%e9%9c%80%e8%a6%81%e5%81%9c%e6%96%b0%e5%9e%8b%e8%96%84%e8%a1%80%e8%97%a5%e5%97%8e\/","title":{"rendered":"Q: \u624b\u8853\u524d\u9700\u8981\u505c\u65b0\u578b\u8584\u8840\u85e5\u55ce?"},"content":{"rendered":"<div class=\"row \"><div class=\"wpv-grid grid-1-1  wpv-first-level first unextended\" style=\"padding-top:0px;padding-bottom:0px\" id=\"wpv-column-9b0ccaba016b9a24d1e8c650b15571ae\" ><p><\/p>\r\n<h2 class=\"wp-block-heading\"><strong>\u91ab\u751f\u7d66\u6211\u5b89\u6392\u4e86\u5927\u8178\u5167\u7aba\u93e1\u505a\u606f\u8089\u5207\u9664\u624b\u8853\uff0c\u4f46\u6211\u6b63\u5728\u670d\u7528\u65b0\u578b\u8584\u8840\u85e5 (New Oral Anticoagulants (NOAC))\u3002\u6211\u9700\u8981\u505c\u85e5\u55ce\uff1f<\/strong><\/h2>\r\n<p><\/p>\r\n<p>\u6297\u51dd\u8840\u85e5\uff0c\u53c8\u7a31\u300c\u8584\u8840\u85e5\u300d\uff0c\u662f\u964d\u4f4e\u8840\u6db2\u51dd\u56fa\u80fd\u529b\u7684\u85e5\u7269\uff0c \u7528\u65bc\u6e1b\u4f4e\u4e2d\u98a8\u53ca\u5176\u4ed6\u8840\u6813\u98a8\u96aa\u3002\u82e5\u8840\u6db2\u51dd\u8840\u529f\u80fd\u4e0d\u6b63\u5e38\uff0c\u624b\u8853\u4e2d\u548c\u624b\u8853\u5f8c\u6d41\u8840\u4f75\u767c\u75c7\u6703\u589e\u52a0\u3002\u4f46\u670d\u7528\u8584\u8840\u85e5\u7684\u60a3\u8005\uff0c\u901a\u5e38\u90fd\u662f\u8eab\u9ad4\u72c0\u6cc1\u5c6c\u65bc\u9ad8\u4e2d\u98a8\u98a8\u96aa\u4eba\u58eb (\u4f8b\u5982\u6709\u5fc3\u623f\u986b\u52d5)\uff0c\u505c\u85e5\u6703\u589e\u52a0\u4e2d\u98a8\u7684\u6a5f\u6703\u3002\u00a0 \u6240\u4ee5\uff0c\u9019\u554f\u984c\u7684\u7b54\u6848\uff0c\u53d6\u6c7a\u65bc\u5e73\u8861\u9019\u5169\u65b9\u9762\u7684\u98a8\u96aa\u3002<\/p>\r\n<p><\/p>\r\n<p>\u4e00\u822c\u4f86\u8aaa\uff0c\u61c9\u5426\u505c\u85e5\u548c\u8853\u524d\u505c\u85e5\u591a\u4e45\u8996\u4e4e (1) \u624b\u8853\u8907\u96dc\u6027 (\u6d41\u8840\u7684\u98a8\u96aa)\uff0c(2) \u8584\u8840\u85e5\u7269\u7a2e\u985e \uff0c(3) \u75c5\u4eba\u814e\u529f\u80fd\u6307\u6578 (\u4ee5Creatine Clearance, CrCl, (ml\/min)\u8a08\u7b97)\u3002\u5f8c\u5169\u8005 (2)\u548c(3)\uff0c\u662f\u63a8\u65b7\u6211\u5011\u8eab\u9ad4\u9700\u591a\u4e45\u624d\u80fd\u628a\u9ad4\u5167\u7684\u85e5\u7269\u6210\u5206\u6392\u51fa\u81f3\u4f4e\u6d41\u8840\u98a8\u96aa\u7684\u6c34\u5e73\u3002<\/p>\r\n<p><\/p>\r\n<p>\u65b0\u578b\u8584\u8840\u85e5(NOAC)\u6709\u56db\u7a2e &#8212; Dabigatran (Pradaxa\u00ae)\u9054\u6bd4\u52a0\u7fa4\u916f , \u00a0Apixaban (Eliquis\u00ae)\u963f\u54cc\u6c99\u73ed,\u00a0 Edoxaban(Lixiana\u00ae)\u827e\u591a\u6c99\u73ed,\u00a0 Rivaroxaban(Xarelto\u00ae)\u5229\u4f10\u6c99\u73ed\u3002<\/p>\r\n<p><\/p>\r\n<p>\u4ee5\u4e0b\u662fERHA 2021 \u6839\u64da\u624b\u8853\u6d41\u8840\u98a8\u96aa\u7684\u8853\u524d\u505c\u85e5\u6307\u5f15\uff1a<\/p>\r\n<p><\/p>\r\n<p><\/p>\r\n<figure class=\"wp-block-table\"><style>\r\n      table,<br \/>      th,<br \/>      td {border: 1px solid black; border-collapse: collapse;<br \/>      }<br \/><\/style>\r\n<table>\r\n<tbody>\r\n<tr>\r\n<td>\u814e\u529f\u80fd\u6307\u6578<br \/>(Creatine Clearance, CrCl)<\/td>\r\n<td>\u4f4e\u6d41\u8840\u98a8\u96aa\u624b\u8853<\/td>\r\n<td>\u9ad8\u6d41\u8840\u98a8\u96aa\u624b\u8853<\/td>\r\n<\/tr>\r\n<tr>\r\n<td colspan=\"3\"><strong>Dabigatran<\/strong><\/td>\r\n<\/tr>\r\n<tr>\r\n<td>&gt;80 ml\/min<\/td>\r\n<td>&gt;=24 \u5c0f\u6642<\/td>\r\n<td>&gt;=48\u5c0f\u6642<\/td>\r\n<\/tr>\r\n<tr>\r\n<td>50-79 ml\/min<\/td>\r\n<td>&gt;=36\u5c0f\u6642<\/td>\r\n<td>&gt;=72\u5c0f\u6642<\/td>\r\n<\/tr>\r\n<tr>\r\n<td>30-49 ml\/min<\/td>\r\n<td>&gt;=48\u5c0f\u6642<\/td>\r\n<td>&gt;=96\u5c0f\u6642<\/td>\r\n<\/tr>\r\n<tr>\r\n<td>&lt;30 ml\/min<\/td>\r\n<td colspan=\"2\">\u4e0d\u61c9\u8a72\u670d\u7528Dabigatran<\/td>\r\n<\/tr>\r\n<tr>\r\n<td colspan=\"3\"><strong>Apixaban, Edoxaban, Rivaroxaban <\/strong><\/td>\r\n<\/tr>\r\n<tr>\r\n<td>&gt; 30 ml\/min<\/td>\r\n<td>&gt;=24\u5c0f\u6642<\/td>\r\n<td>&gt;=48\u5c0f\u6642<\/td>\r\n<\/tr>\r\n<tr>\r\n<td>15-29 ml\/min<\/td>\r\n<td>&gt;=36\u5c0f\u6642<\/td>\r\n<td>&gt;=48\u5c0f\u6642<\/td>\r\n<\/tr>\r\n<tr>\r\n<td>&lt;15 ml\/min<\/td>\r\n<td colspan=\"2\">\u4e0d\u61c9\u8a72\u670d\u7528Apixaban\/ Edoxaban\/ Rivaroxaban<\/td>\r\n<\/tr>\r\n<\/tbody>\r\n<\/table>\r\n<\/figure>\r\n<p><\/p>\r\n<p>\u5927\u8178\u5167\u7aba\u93e1\u4f75\u606f\u8089\u5207\u9664\u624b\u8853\u5c6c\u65bc\u9ad8\u6d41\u8840\u98a8\u96aa\u624b\u8853\u3002\u6309\u7167\u9019\u5716\u8868\uff0c\u82e5\u60a8\u670d\u7528\u7684\u662fDabigatran, \u53c8\u82e5\u60a8\u814e\u529f\u80fd\u662f 60 ml\/min\uff0c\u90a3\u60a8\u61c9\u5728\u8853\u524d72\u5c0f\u6642\u505c\u85e5\u3002\u82e5\u60a8\u670d\u7528\u7684\u662fApixaban, \u53c8\u82e5\u60a8\u814e\u529f\u80fd\u662f20 ml\/min\uff0c\u90a3\u60a8\u61c9\u5728\u8853\u524d48\u5c0f\u6642\u505c\u85e5\u3002\u5982\u6b64\u985e\u63a8\u3002<\/p>\r\n<p><\/p>\r\n<p>\u5207\u8a18\uff0c\u624b\u8853\u5f8c\uff0c\u82e5\u91ab\u751f\u5224\u65b7\u6b62\u8840\u5df2\u7a69\u59a5\uff0c\u61c9\u6309\u6307\u793a\u6062\u5fa9\u670d\u7528\u8584\u8840\u85e5\u3002<\/p>\r\n<p><\/p>\r\n<p>***\u4ee5\u4e0a\u8cc7\u6599\u50c5\u4f9b\u53c3\u8003\uff0c\u75c5\u4eba\u4e0d\u61c9\u81ea\u884c\u6c7a\u5b9a\uff0c\u800c\u61c9\u8207\u91ab\u751f\u6e9d\u901a\uff0c\u8b93\u91ab\u751f\u6309\u60a8\u8eab\u9ad4\u72c0\u614b\u548c\u624b\u8853\u985e\u578b\u6c7a\u5b9a\u3002<\/p>\r\n<p><\/p>\r\n<p>\u53c3\u8003\u6587\u737b\uff1aSteffel J, et al. 2021 European Heart Rhythm Association Practical Guide on the Use of Non-Vitamin K Antagonist Oral Anticoagulants in Patients with Atrial Fibrillation [published online ahead of print, 2021 Apr 25] [published correction appears in Europace. 2021 Jun 28;:].\u00a0<em>Europace<\/em>. 2021;euab065. doi:10.1093\/europace\/euab065<\/p>\r\n<p><\/p>\r\n<p><\/p>\r\n<figure class=\"wp-block-image size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-25534\" src=\"https:\/\/www.stroke.org.hk\/home\/wp-content\/uploads\/2021\/06\/NOAC-Fig-14-short.jpeg\" alt=\"\" width=\"325\" height=\"155\" srcset=\"https:\/\/www.stroke.org.hk\/home\/wp-content\/uploads\/2021\/06\/NOAC-Fig-14-short.jpeg 520w, https:\/\/www.stroke.org.hk\/home\/wp-content\/uploads\/2021\/06\/NOAC-Fig-14-short-300x143.jpeg 300w, https:\/\/www.stroke.org.hk\/home\/wp-content\/uploads\/2021\/06\/NOAC-Fig-14-short-360x171.jpeg 360w, https:\/\/www.stroke.org.hk\/home\/wp-content\/uploads\/2021\/06\/NOAC-Fig-14-short-262x124.jpeg 262w\" sizes=\"auto, (max-width: 325px) 100vw, 325px\" \/><\/figure>\r\n<p><\/p>\r\n<p>(\u52de \u6167 \u5a77 \u91ab \u751f)<\/p>\r\n<p><\/p><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>\u91ab\u751f\u7d66\u6211\u5b89\u6392\u4e86\u5927\u8178\u5167\u7aba\u93e1\u505a\u606f\u8089\u5207\u9664\u624b\u8853\uff0c\u4f46\u6211\u6b63\u5728\u670d\u7528\u65b0\u578b\u8584\u8840\u85e5 (New Oral Anticoagulants (NOAC))\u3002\u6211\u9700\u8981\u505c\u85e5\u55ce\uff1f \u6297\u51dd\u8840\u85e5\uff0c\u53c8\u7a31\u300c\u8584\u8840\u85e5\u300d\uff0c\u662f\u964d\u4f4e\u8840\u6db2\u51dd\u56fa\u80fd\u529b\u7684\u85e5\u7269\uff0c \u7528\u65bc\u6e1b\u4f4e\u4e2d\u98a8\u53ca\u5176\u4ed6\u8840\u6813\u98a8\u96aa\u3002\u82e5\u8840\u6db2\u51dd\u8840\u529f\u80fd\u4e0d\u6b63\u5e38\uff0c\u624b\u8853\u4e2d\u548c\u624b\u8853\u5f8c\u6d41\u8840\u4f75\u767c\u75c7\u6703\u589e\u52a0\u3002\u4f46\u670d\u7528\u8584\u8840\u85e5\u7684\u60a3\u8005\uff0c\u901a\u5e38\u90fd\u662f\u8eab\u9ad4\u72c0\u6cc1\u5c6c\u65bc\u9ad8\u4e2d\u98a8\u98a8\u96aa\u4eba\u58eb (\u4f8b\u5982\u6709\u5fc3\u623f\u986b\u52d5)\uff0c\u505c\u85e5\u6703\u589e\u52a0\u4e2d\u98a8\u7684\u6a5f\u6703\u3002\u00a0 \u6240\u4ee5\uff0c\u9019\u554f\u984c\u7684\u7b54\u6848\uff0c\u53d6\u6c7a\u65bc\u5e73\u8861\u9019\u5169\u65b9\u9762\u7684\u98a8\u96aa\u3002 \u4e00\u822c\u4f86\u8aaa\uff0c\u61c9\u5426\u505c\u85e5\u548c\u8853\u524d\u505c\u85e5\u591a\u4e45\u8996\u4e4e (1) \u624b\u8853\u8907\u96dc\u6027 (\u6d41\u8840\u7684\u98a8\u96aa)\uff0c(2) \u8584\u8840\u85e5\u7269\u7a2e\u985e \uff0c(3) \u75c5\u4eba\u814e\u529f\u80fd\u6307\u6578 (\u4ee5Creatine Clearance, CrCl, (ml\/min)\u8a08\u7b97)\u3002\u5f8c\u5169\u8005 (2)\u548c(3)\uff0c\u662f\u63a8\u65b7\u6211\u5011\u8eab\u9ad4\u9700\u591a\u4e45\u624d\u80fd\u628a\u9ad4\u5167\u7684\u85e5\u7269\u6210\u5206\u6392\u51fa\u81f3\u4f4e\u6d41\u8840\u98a8\u96aa\u7684\u6c34\u5e73\u3002 \u65b0\u578b\u8584\u8840\u85e5(NOAC)\u6709\u56db\u7a2e &#8212; Dabigatran (Pradaxa\u00ae)\u9054\u6bd4\u52a0\u7fa4\u916f , \u00a0Apixaban (Eliquis\u00ae)\u963f\u54cc\u6c99\u73ed,\u00a0 Edoxaban(Lixiana\u00ae)\u827e\u591a\u6c99\u73ed,\u00a0 Rivaroxaban(Xarelto\u00ae)\u5229\u4f10\u6c99\u73ed\u3002&#8230;<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_coblocks_attr":"","_coblocks_dimensions":"","_coblocks_responsive_height":"","_coblocks_accordion_ie_support":"","_EventAllDay":false,"_EventTimezone":"","_EventStartDate":"","_EventEndDate":"","_EventStartDateUTC":"","_EventEndDateUTC":"","_EventShowMap":false,"_EventShowMapLink":false,"_EventURL":"","_EventCost":"","_EventCostDescription":"","_EventCurrencySymbol":"","_EventCurrencyCode":"","_EventCurrencyPosition":"","_EventDateTimeSeparator":"","_EventTimeRangeSeparator":"","_EventOrganizerID":[],"_EventVenueID":[],"_OrganizerEmail":"","_OrganizerPhone":"","_OrganizerWebsite":"","_VenueAddress":"","_VenueCity":"","_VenueCountry":"","_VenueProvince":"","_VenueState":"","_VenueZip":"","_VenuePhone":"","_VenueURL":"","_VenueStateProvince":"","_VenueLat":"","_VenueLng":"","_VenueShowMap":false,"_VenueShowMapLink":false,"footnotes":""},"categories":[87],"tags":[],"class_list":["post-25483","post","type-post","status-publish","format-standard","hentry","category-faq"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.7 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Q: \u624b\u8853\u524d\u9700\u8981\u505c\u65b0\u578b\u8584\u8840\u85e5\u55ce? - Hong Kong Stroke Society Website<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.stroke.org.hk\/home\/2021\/07\/10\/q-\u624b\u8853\u524d\u9700\u8981\u505c\u65b0\u578b\u8584\u8840\u85e5\u55ce\/\" \/>\n<meta property=\"og:locale\" content=\"en_GB\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Q: \u624b\u8853\u524d\u9700\u8981\u505c\u65b0\u578b\u8584\u8840\u85e5\u55ce? - Hong Kong Stroke Society Website\" \/>\n<meta property=\"og:description\" content=\"\u91ab\u751f\u7d66\u6211\u5b89\u6392\u4e86\u5927\u8178\u5167\u7aba\u93e1\u505a\u606f\u8089\u5207\u9664\u624b\u8853\uff0c\u4f46\u6211\u6b63\u5728\u670d\u7528\u65b0\u578b\u8584\u8840\u85e5 (New Oral Anticoagulants (NOAC))\u3002\u6211\u9700\u8981\u505c\u85e5\u55ce\uff1f \u6297\u51dd\u8840\u85e5\uff0c\u53c8\u7a31\u300c\u8584\u8840\u85e5\u300d\uff0c\u662f\u964d\u4f4e\u8840\u6db2\u51dd\u56fa\u80fd\u529b\u7684\u85e5\u7269\uff0c \u7528\u65bc\u6e1b\u4f4e\u4e2d\u98a8\u53ca\u5176\u4ed6\u8840\u6813\u98a8\u96aa\u3002\u82e5\u8840\u6db2\u51dd\u8840\u529f\u80fd\u4e0d\u6b63\u5e38\uff0c\u624b\u8853\u4e2d\u548c\u624b\u8853\u5f8c\u6d41\u8840\u4f75\u767c\u75c7\u6703\u589e\u52a0\u3002\u4f46\u670d\u7528\u8584\u8840\u85e5\u7684\u60a3\u8005\uff0c\u901a\u5e38\u90fd\u662f\u8eab\u9ad4\u72c0\u6cc1\u5c6c\u65bc\u9ad8\u4e2d\u98a8\u98a8\u96aa\u4eba\u58eb (\u4f8b\u5982\u6709\u5fc3\u623f\u986b\u52d5)\uff0c\u505c\u85e5\u6703\u589e\u52a0\u4e2d\u98a8\u7684\u6a5f\u6703\u3002\u00a0 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